Secretory endometrium dating


09-Aug-2017 21:50

Typically, a weak pseudodecidual response will occur (Fig. The microscopic appearance of the endometrium exposed to oral contraceptives varies, depending on the dose of progestin.

Typically, stroma having a weak progestin effect surrounds simple, straight, widely spaced, and inactive-appearing endometrial glands.

The endometrium usually atrophies, but variable hyperplasia and, rarely, adenocarcinoma can occur due to the weak estrogen agonist effect.

Chronic endometritis is sometimes demonstrated in endometrial biopsies for infertility or recurrent pregnancy loss.

With oral contraceptives, the progestin effect dominates because progestins decrease estrogen receptors. The appearance of the stroma depends on the dose of progestin.Recently a detailed analysis on endometrial dating demonstrated that the histologic criteria used are not as temporally distinct as originally thought, and thus do not provide an accurate method to detect a luteal phase defect.In one study, approximately 20% of fertile couples had a delay of more than 2 days.In addition, the original description fixed the time of ovulation with the onset of the period after the biopsy.



It is asserted that examination of the endometrium during the secretory phase yields more information about the time of ovulation, degree of progestational change, and normality of the endometrium than any other test used in sterility studies. Attention to qualitative changes in 8 morphological factors is most useful in dating.… continue reading »


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Dec 21, 2017. Request PDF Histologic dating of. on ResearchGate, the professional network for scientists. Histologic dating of the endometrium accuracy, reproducibility, and practical value. Article in Advances. To refine or redefine the traditional histologic criteria used to date the secretory phase endometrium.… continue reading »


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Biopsies were performed on luteal phase days 6 and 10, according to the day of LH peak, which provides the best correlation for histological dating.3,9,13 Considering that the endometrial secretory phase is induced by progesterone, and the synthesis of this hormone is LH-dependent, taking the LH peak day as the.… continue reading »


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